Pharmacodynamic and pharmacokinetic processes

Pharmacodynamic and pharmacokinetic processes:

general principles

• pharmacokinetics: absorption, distribution, metabolism, excretion, dosage intervals
• mechanisms of drug action, structure-activity relationships (including anticancer drugs)
• concentration- and dose-effect relationships, types of agonists and antagonists and their actions
• individual factors altering pharmacokinetics and pharmacodynamics
• mechanisms of drug adverse effects, overdosage, toxicology
• mechanisms of drug interactions
• regulatory issues
• signal transduction, including structure/function of all components of signal transduction pathway such as receptors, ligands
• cell cycle/cell cycle regulation.

Source: http://www.usmleworldwide.com/blog/?p=179